Mh. Zareie et al., IMAGING OF LIPOSOMES BY SCANNING-TUNNELING-MICROSCOPY, Artificial cells, blood substitutes, and immobilization biotechnology, 24(5), 1996, pp. 525-531
In this study, unilamellar and multilamellar liposomes consisting of d
ipalmitoylphosphatidylcholine, cholesterol and dicetylphosphate were p
repared. Scanning tunneling microscopy images of these liposomes on hi
ghly oriented pyrolytic graphite surfaces were obtained. It was observ
ed that scanning tunnelling microscopy can be succesfully used for hig
h-resolution, three-dimensional structure analysis of liposomes under
very mild conditions.