HIV-ASSOCIATED DEMENTIA AND RELATED DISORDERS

HIV infection is associated with an increased risk of primary cognitiv e disorders. These can have important implications for quality of life and the care of people with the disease. In this paper, we review the concepts, terminology and diagnosis of HIV-associated dementia and re lated disorders. This is followed by discussion of their epidemiology, course and prognosis. The concept of HIV-associated minor cognitive i mpairment is considered, as well as the evidence for its presence in N N symptomatic and asymptomatic individuals. The management of HIV-asso ciated dementia is considered next, with discussion of pharmacological , psychological and social interventions. Finally, the question of the prevention of HIV-associated dementia is reviewed.