A SIMPLE, CIP-BASED NOTATION SYSTEM FOR THE UNAMBIGUOUS SPECIFICATIONOF ASYMMETRIC REACTIONS

Authors
AVALOS M BABIANO R CINTAS P JIMENEZ JL PALACIOS JC
Citation
M. Avalos et al., A SIMPLE, CIP-BASED NOTATION SYSTEM FOR THE UNAMBIGUOUS SPECIFICATIONOF ASYMMETRIC REACTIONS, Tetrahedron : asymmetry, 7(8), 1996, pp. 2333-2342
Citations number
56
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
8
Year of publication
1996
Pages
2333 - 2342
Database
ISI
SICI code
0957-4166(1996)7:8<2333:ASCNSF>2.0.ZU;2-9
Abstract
A set of stereochemical rules based on the CIP configurational descrip tors have been proposed for the specification of the stereochemical ou tcome of asymmetric transformations. This simple and unambiguous syste m denotes the steric approach involving prochiral faces and stereogeni c centers of reactants, either in enantio- or diastereoselective synth esis. The descriptors form chiral codes of symbols and numbers, which are susceptible of computerization. A brief discussion and comparison with other terms currently employed in dynamic stereochemistry are als o given. Copyright (C) 1996 Elsevier Science Ltd