Following failure of conventional therapy for reflux oesophagitis, 15
children were treated with omeprazole 20 mg daily for a period of up t
o three months initially. Treatment resulted in a marked symptomatic i
mprovement as measured by incidence of pain, vomiting, dysphagia and h
aematemesis. Four children failed treatment and required fundoplicatio
n. No complications from the use of omeprazole were recorded and some
children have continued long-term treatment.