PLASMA FOLLISTATIN CONCENTRATIONS INCREASE FOLLOWING LIPOPOLYSACCHARIDE ADMINISTRATION IN SHEEP

Authors
KLEIN R CLARKE IJ HEDGER MP ROBERTSON DM
Citation
R. Klein et al., PLASMA FOLLISTATIN CONCENTRATIONS INCREASE FOLLOWING LIPOPOLYSACCHARIDE ADMINISTRATION IN SHEEP, Clinical and experimental pharmacology and physiology, 23(8), 1996, pp. 754-755
Citations number
5
Categorie Soggetti
Pharmacology & Pharmacy",Physiology
Journal title
Clinical and experimental pharmacology and physiology → ACNP
ISSN journal
03051870
Volume
23
Issue
8
Year of publication
1996
Pages
754 - 755
Database
ISI
SICI code
0305-1870(1996)23:8<754:PFCIFL>2.0.ZU;2-U
Abstract
1. The effect of inflammation induced by lipopolysaccharide (LPS) inje ction on plasma follistatin (FS) concentrations was investigated. 2. P lasma FS and tumour necrosis factor-alpha concentrations increase foll owing LPS administration in ewes. 3. The rise in FS is similar, but mo re sustained, to that reviously observed after surgery. 4. These resul ts indicate a possible functional link between FS, inflammation and th e acute-phase response.