Pa. Tsonis et al., CAN INSIGHTS INTO URODELE LIMB REGENERATION BE ACHIEVED WITH CELL-CULTURES AND RETROVIRUSES, The International journal of developmental biology, 40(4), 1996, pp. 813-816
Recent advances in the field of amphibian limb regeneration have provi
ded insights into its cellular and molecular events. This review summa
rizes the development of cell lines from limb tissues and their applic
ation to the study of transdifferentiation and limb regeneration. In a
ddition, the availability of suitable retroviral vectors for salamande
rs is discussed for it has opened new avenues for experimentation at t
he molecular level.