Ma. Kuhn et al., MANAGEMENT OF PEDIATRIC-PATIENTS WITH ISOLATED VALVAR AORTIC-STENOSISBY BALLOON AORTIC VALVULOPLASTY, Catheterization and cardiovascular diagnosis, 39(1), 1996, pp. 55-61
Moderate to severe aortic stenosis in children requires an initial pro
cedure to improve the stenosis and often additional procedures for rec
urrent stenosis or aortic insufficiency before adulthood. The purpose
of this study was to evaluate children who underwent balloon valvulopl
asty and were followed with a specific management plan, Twenty-two chi
ldren with aortic stenosis underwent balloon valvuloplasty and were fo
llowed on a regular basis, Repeat valvuloplasty was performed if indic
ated, The initial gradient was reduced from 63 +/- 9 mmHg to 28 +/- 8
mmHg (P < 0.001), There were no deaths and only one major complication
, which had no sequelae. Average follow-up was 61 +/- 23 months. Three
patients required valve replacement 39-76 months after valvuloplasty
for progressive insufficiency, Seven patients underwent successful rep
eat valvuloplasty, The overall probability of survival without surgica
l intervention was 75% at 100 months, Balloon valvuloplasty is an effe
ctive intermediate palliation for aortic stenosis and is an acceptable
alternative to surgical valvotomy. Repeat valvuloplasty is successful
without additional risk. In a subgroup of patients, aortic insufficie
ncy is progressive and will require surgical intervention. (C) 1996 Wi
ley-Liss, Inc.