D. Lieberman et al., MYCOPLASMA-PNEUMONIAE COMMUNITY-ACQUIRED PNEUMONIA - A REVIEW OF 101 HOSPITALIZED ADULT PATIENTS, Respiration, 63(5), 1996, pp. 261-266
The features of community-acquired Mycoplasma pneumoniae pneumonia (MP
-CAP) were assessed in a prospective study of 101 adults who were hosp
italized over the course of 1 year, and were compared with 245 patient
s who were hospitalized during the same period of time with community-
acquired pneumonia (CAP) not caused by M. pneumoniae (non-MP-CAP). MP
was the second most common etiology (29.2%) in all CAP patients, and t
he most common etiological agent (43.2%) in the 17- to 44-year age gro
up. In 65 patients (64.3%) at least one other pathogen was identified
for CAP in addition to MP. Although the disease was most prevalent amo
ng younger patients, it also involved older and even elderly patients.
Compared to non-MP-CAP patients, the severity of disease was signific
antly lower on average in the MP-CAP group and the length of hospitali
zation was significantly shorter. Radiologic findings were the same in
the two groups. Twenty-two MP-CAP patients recovered without receivin
g the treatment which is recognized as effective in this disease. We c
oncluded that (I) in most patients with MP-CAP a second CAP pathogen c
an be identified serologically, (2) MP-CAP cannot be differentiated fr
om non-MP-CAP on the basis of clinical, radiologic, or routine laborat
ory tests, and (3) in some MP-CAP patients the disease is self-limited
, and in these patients the usefulness of standard antibiotic therapy
is doubtful.