Fj. Zawacki et Mt. Crimmins, A CONVENIENT SYNTHESIS OF UNSYMMETRICAL, SUBSTITUTED GAMMA-PYRONES FROM MELDRUMS ACID, Tetrahedron letters, 37(36), 1996, pp. 6499-6502
A unique approach to the synthesis of mono and disubstituted gamma-pyr
ones from acylated Meldrum's acid and vinyl ethers has been developed.
The convenient one pot synthesis of these versatile polyketide equiva
lents is accomplished without strong bare or low temperatures. Copyrig
ht (C) 1996 Elsevier Science Ltd