FIRST EFFICIENT PALLADIUM-CATALYZED HECK REACTIONS OF ARYL BROMIDES WITH ALKYL METHACRYLATE

Authors
BELLER M RIERMEIER TH
Citation
M. Beller et Th. Riermeier, FIRST EFFICIENT PALLADIUM-CATALYZED HECK REACTIONS OF ARYL BROMIDES WITH ALKYL METHACRYLATE, Tetrahedron letters, 37(36), 1996, pp. 6535-6538
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
36
Year of publication
1996
Pages
6535 - 6538
Database
ISI
SICI code
0040-4039(1996)37:36<6535:FEPHRO>2.0.ZU;2-1
Abstract
An efficient palladium-catalyzed coupling reaction of aryl bromides wi th butyl methacrylate has been developed. Depending on the reaction co nditions various amounts of butyl 3-aryl-2-methylpropenoate and butyl 3-aryl-2-methyliden-propenoate as well as double arylated products wer e produced. Superior turn over numbers up to 8300 and turn over freque ncies up to 1000 h(-1) for Heck reactions of aryl bromides with methac rylic acid ester have been obtained for the first rime. Copyright (C) 1996 Elsevier Science Ltd