A BIOPHYSICAL MODEL FOR DEFIBRILLATION OF CARDIAC TISSUE

Authors
KEENER JP PANFILOV AV
Citation
Jp. Keener et Av. Panfilov, A BIOPHYSICAL MODEL FOR DEFIBRILLATION OF CARDIAC TISSUE, Biophysical journal, 71(3), 1996, pp. 1335-1345
Citations number
19
Categorie Soggetti
Biophysics
Journal title
Biophysical journal → ACNP
ISSN journal
00063495
Volume
71
Issue
3
Year of publication
1996
Pages
1335 - 1345
Database
ISI
SICI code
0006-3495(1996)71:3<1335:ABMFDO>2.0.ZU;2-Z
Abstract
We propose a new model for electrical activity of cardiac tissue that incorporates the effects of cellular microstructure. As such, this mod el provides insight into the mechanism of direct stimulation and defib rillation of cardiac tissue after injection of large currents. To illu strate the usefulness of the model, numerical stimulations are used to show the difference between successful and unsuccessful defibrillatio n of large pieces of tissue.