DISEASE EXTINCTION AND COMMUNITY SIZE - MODELING THE PERSISTENCE OF MEASLES

Citation
Mj. Keeling et Bt. Grenfell, DISEASE EXTINCTION AND COMMUNITY SIZE - MODELING THE PERSISTENCE OF MEASLES, Science, 275(5296), 1997, pp. 65-67
Citations number
31
Categorie Soggetti
Multidisciplinary Sciences
Journal title
ISSN journal
00368075
Volume
275
Issue
5296
Year of publication
1997
Pages
65 - 67
Database
ISI
SICI code
0036-8075(1997)275:5296<65:DEACS->2.0.ZU;2-I
Abstract
A basic issue in ecology is the relation between extinction and popula tion size. One of the dearest manifestations of a population threshold for extinction is the critical community size below which infections like measles do not persist. The current generation of stochastic mode ls overestimates the observed critical community size for measles, gen erating much less persistence of infection than is observed. The inclu sion of a more biologically realistic model for the duration of infect ion produced a much closer fit to the actual critical community size a nd explains previously undescribed high-frequency oscillations in meas les incidence.