Sf. Dowell et al., RESPIRATORY SYNCYTIAL VIRUS IS AN IMPORTANT CAUSE OF COMMUNITY-ACQUIRED LOWER RESPIRATORY-INFECTION AMONG HOSPITALIZED ADULTS, The Journal of infectious diseases, 174(3), 1996, pp. 456-462
Respiratory syncytial virus (RSV), the most important cause of lower r
espiratory disease in infants and young children, is rarely considered
among the causes for community-acquired lower respiratory infection i
n adults. All noninstitutionalized adults hospitalized with community-
acquired pneumonia in two Ohio counties were evaluated between Decembe
r 1990 and May 1992. Fifty-three (4.4%) of 1195 adults admitted during
the RSV seasons and 4 (1.0%) of 390 in the off-season had serologic e
vidence of RSV infection, making RSV one of the four most common patho
gens identified, RSV-infected patients had clinical features (e.g., wh
eezing and rhonchi) that distinguished them from all non-RSV-infected
patients and other features (e.g., nonelevated white blood cell counts
) that distinguished them from those infected with bacterial or atypic
al agents, However, RSV infection was not diagnosed during hospitaliza
tion for any of the 57 RSV-infected patients. RSV should be considered
in the differential diagnosis for adults hospitalized between Novembe
r and April with community-acquired lower respiratory infection.