This study assesses the diagnostic capability of statistically defined
prediction regions, developed by a 'bootstrap' method, for assessing
the curves of angular rotation of joints in children as they walk. The
prediction regions had been previously developed in the authors' labo
ratory from a study of 309 normal children. The goal of tile present s
tudy was to determine whether these computer-generated prediction regi
ons could be used as a screen in clinical gait analysis, to determine
whether a movement falls outside the normal range of variability. Kine
matic analysis of 38 consecutive children referred to the: motion anal
ysis laboratory fur clinical gait assessment provided 912 curves of lo
wer-extremity joint angle dynamics. An experienced observer first insp
ected the patients' curves with mean normal curves superimposed and de
signated the curves as normal or abnormal. The performance of the comp
uter-generated prediction regions was judged by comparison with the ex
perienced observer's designations. The prediction regions were found t
o have a high sensitivity (81%), indicating that they can be used as a
n initial screen to identify deficits in lower Limb function.