POLYARTHRITIS ASSOCIATED WITH MYELODISPLA STIC SYNDROMES

Citation
Ic. Mendez et al., POLYARTHRITIS ASSOCIATED WITH MYELODISPLA STIC SYNDROMES, Revista Clinica Espanola, 196(8), 1996, pp. 539-541
Citations number
16
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00142565
Volume
196
Issue
8
Year of publication
1996
Pages
539 - 541
Database
ISI
SICI code
0014-2565(1996)196:8<539:PAWMSS>2.0.ZU;2-H
Abstract
Recently, different rheumatic manifestations have been reported in ass ociation with myelodysplastic syndromes (MDS). The objective of the pr esent report was to know the prevalence and characteristics of joint i nflammatory manifestations associated with MDS in our environment. Thr ee cases were found in the review of 55 patients with RIDS diagnosed i n our institution in the last three years, The three patients had chro nic non-erosive polyarthritis, with a poor response to non-steroidal a nti-inflammatory drugs and required intermediate doses of glucocortico ids for its control, The arthritis was present in two patients at bloo d disease diagnosis. The prevalence of arthritis associated with MDS i n our series was 5.4% (95% CI: 1.1% to 15.1%). Articular symptoms may be present before the hematological diagnosis; therefore, MDS must be considered in the differential diagnosis of late onset polyarthritis, particularly when associated with cytopenia, Glucocorticoid therapy at intermediate doses is usually required to control the articular sympt oms.