Information concerning the disease burden of rotavirus, particularly i
n developing countries, has important implications for the use and for
monitoring the impact of rotavirus vaccines. Although rotavirus has b
een recognized as the most frequent cause of hospitalization in the wo
rld, national estimates and specific information about the incidence o
f hospitalization for rotavirus gastroenteritis are very limited. Cons
equently, estimates of the incidence of hospitalization among children
during the first 2 years of life in Venezuela were determined by extr
apolation of data from a community-based study carried out in Caracas.