EOSINOPHIL PRIMING BY CYTOKINES - FROM CELLULAR SIGNAL TO IN-VIVO MODULATION

Authors
KOENDERMAN L VANDERBRUGGEN T SCHWEIZER RC WARRINGA RAJ COFFER P CALDENHOVEN E LAMMERS JWJ RAAIJMAKERS JAM
Citation
L. Koenderman et al., EOSINOPHIL PRIMING BY CYTOKINES - FROM CELLULAR SIGNAL TO IN-VIVO MODULATION, The European respiratory journal, 9, 1996, pp. 119-125
Citations number
83
Categorie Soggetti
Respiratory System
Journal title
The European respiratory journal → ACNP
ISSN journal
09031936
Volume
9
Year of publication
1996
Supplement
22
Pages
119 - 125
Database
ISI
SICI code
0903-1936(1996)9:<119:EPBC-F>2.0.ZU;2-L
Abstract
Eosinophils play an important role in the effector phase of allergic i nflammation. This review will focus on the conversion of the unprimed eosinophil phenotype in the peripheral blood of normal individuals to the primed phenotype found in the peripheral blood and tissues of alle rgic patients, a phenomenon called priming, Recent data on the signals initiated after cytokine receptor activation on eosinophils will be r eviewed.