Before starting treatment of chronic glomerulonephritis it is desirabl
e to determine the patient's drug sensitivity in vitro because in the
absence of such sensitivity chemotherapy should be preceded by immunom
odulation with tactivin or thymalin and 3-5 sessions of plasmapheresis
to stimulate drug sensitivity. Further measures include prednisolone
or cyclophosphamide intravenously for 3-5 days in a dose 300-500 follo
wed by oral administration. Active treatment lasts for 4-8 weeks. Afte
r that the patients receive maintenance for 1-2 years.