Fu. Dzgoeva et al., NEW APPROACHES TO PATHOGENETIC THERAPY AN D PREVENTION OF ACUTE-RENAL-FAILURE DUE TO RADIO-OPAQUE SUBSTANCES, Terapevticeskij arhiv, 68(6), 1996, pp. 37-40
authors analyze causes, mechanisms underlying acute renal failure (ARF
) attributed to tests with application of radioopaque substances and r
esults of ARF treatment in 12 ARF patients and on Wistar rats models.
It is inferred that AFR is a frequent and severe complication of the a
bove tests which may be treated successfully by early application of d
ialysis, filtration, sorption, plasmapheresis techniques. Disorders of
calcium metabolism and their correction contribute to ARF onset. Radi
o-opaque substances have essential inhibiting action on nitrogen oxide
synthesis in the kidneys of experimental animals.