NEW APPROACHES TO PATHOGENETIC THERAPY AN D PREVENTION OF ACUTE-RENAL-FAILURE DUE TO RADIO-OPAQUE SUBSTANCES

authors analyze causes, mechanisms underlying acute renal failure (ARF ) attributed to tests with application of radioopaque substances and r esults of ARF treatment in 12 ARF patients and on Wistar rats models. It is inferred that AFR is a frequent and severe complication of the a bove tests which may be treated successfully by early application of d ialysis, filtration, sorption, plasmapheresis techniques. Disorders of calcium metabolism and their correction contribute to ARF onset. Radi o-opaque substances have essential inhibiting action on nitrogen oxide synthesis in the kidneys of experimental animals.