President Clinton's charge to the Advisory Committee on Human Radiatio
n Experiments included the identification of ethical and legal standar
ds for evaluating government-sponsored radiation experiments conducted
during the Cold War. In this paper, we review the traditional account
of the history of American research ethics, and then highlight and ex
plain the significance of a number of the Committee's historical findi
ngs as they relate to this account. These findings include both the na
tional defense establishment's struggles with legal and insurance issu
es concerning human experiments, and the medical profession's perspect
ive on human experimentation in the years following the Nuremberg Medi
cal Trials. We conclude that the Committee's work both enriches the tr
aditional view of the history of research ethics and opens important n
ew areas for study.