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Several improvements of the basic reaction between elastin-solubilized
peptides and type I + III collagens are presented. They concern the p
rior incubation of the proteins in an adequate medium as well as the a
ddition of heparan sulphate or hyaluronic acid (HA) and the consequent
effects on the physical properties of yielded matrices. The addition
of HA in small amounts enabled us to make membranes with good performa
nces. (C) 1996 Elsevier Science Limited.