In vivo dosimetry is recommended as part of the quality control proced
ure for treatment verification in radiation therapy. Using thermolumin
escence, such controls are planned in the p(65)+Be neutron and 85 MeV
proton beams produced at the cyclotron at Louvain-La-Neuve and dedicat
ed to therapy applications. A preliminary study of the peak 3 (150 deg
rees C) and peak 5 (250 degrees C) response of CaF2:Tm (TLD-300) to ne
utron and proton beams aimed to analyse the effect of different radiat
ion qualities on the dosimetric behaviour of the detector irradiated i
n phantom. To broaden the range of investigation, the study was extend
ed to an experimental C-12 heavy ion beam (95 MeV/nucleon). The peak 3
and 5 sensitivities in the neutron beam, compared to Co-60, varied li
ttle with depth. A major change of peak 5 sensitivity was observed for
samples positioned under five leaves of the multi-leaf collimator. Wh
ile peak 3 sensitivity was constant with depth in the unmodulated prot
on beam, peak 5 sensitivity increased by 15%. Near the Bragg peak, pea
k 3 showed the highest decrease of sensitivity. In the modulated proto
n beam, the sensitivity values were not significantly smaller than tho
se measured in the unmodulated beam far from the Bragg peak region. Th
e ratio of the heights of peak 3 and peak 5 decreased by 70% from the
Co-60 reference radiation to the C-12 heavy-ion beam. This parameter w
as strongly correlated with the change of radiation quality.