Conscious sedation with subanaesthetic doses of propofol is an effecti
ve technique for the management of highly anxious patients in dentistr
y. Prolonged administration of propofol to achieve conscious sedation
in spontaneously breathing patients without an airway adjunct has not
been been reported previously. We describe the management of target-co
ntrolled conscious sedation, with propofol for 21 h in a patient under
going gynaecological radiotherapy.