THE EFFECT OF PRETREATMENT WITH KETOROLAC ON PAIN DURING INTRAVENOUS-INJECTION OF PROPOFOL

A randomised, double-blind, controlled trial was undertaken to compare three different methods of reducing pain during the intravenous injec tion of propofol. In 101 patients undergoing daycase surgery, verbal r ating scores for pain during injection of propofol were compared immed iately after intravenous pretreatment with ketorolac IO mg, lignocaine 10 mg or saline. Neither pain during injection (p = 0.129), nor venou s sequelae at 7 clays postoperatively were significantly different bet ween the three treatments. Pain during propofol injection remains a co nfounding clinical problem.