CHLORINATED-HYDROCARBON SOLVENTS AND BILIARY-PANCREATIC CANCER - REPORT OF 3 CASES

This paper describes three men, aged 45 years or younger, who develope d cholangio, ampullary, and pancreatic cancer after prolonged heavy ex posure to trichlorinated hydrocarbon solvents. Two of these patients h ad exposure to other potential carcinogens, and one had a strong famil y history of cancer. The association between chlorinated hydrocarbons and biliary-pancreatic cancer has also been suggested by other reports in the recent literature. Exposure to trichlorinated hydrocarbon solv ents is a risk factor for the development of biliary and pancreatic ca ncer. (C) 1996 Wiley-Liss, Inc.