Secondary plant metabolites and their degradation products are importa
nt in all agroecosystems including those with forage crops. Allelopath
y affects cropping systems and interseeding of one species into establ
ished sods of another. Autotoxicity and heterotoxicity are types of al
lelopathy. Alfalfa (Medicago saliva L.) has been investigated as both
an autotoxic and heterotoxic species. Reestablishment of alfalfa immed
iately after alfalfa has usually resulted in poor stands due to autoto
xicity, and several other forage species also exhibit autotoxicity. Ma
ny forage species have shown heterotoxicity, both between forage speci
es and weed species. Several investigators have identified various all
elochemicals and/or families of allelochemicals as being responsible f
or allelopathic reactions. Identifying such chemicals would aid in dev
eloping resistant forage cultivars and in maintaining a productive and
profitable crop. Crop rotation, cover-crop management, interplanting,
double cropping, no-till planting, and nonrotational cropping systems
are involved with allelopathic effects. Some alfalfa cultivars posses
s some resistance to these allelochemicals. Therefore, a breeding prog
ram could provide resistant germplasms. Various forage grasses and som
e weed species have demonstrated allelopathic effects on alfalfa, and
alfalfa has allelopathic effects on some weed species. This alone may
provide an insight for herbicide studies in alfalfa production.