W. Hemmer et al., ALLERGIC CONTACT-DERMATITIS TO ARTIFICIAL FINGERNAILS PREPARED FROM UV LIGHT-CURED ACRYLATES, Journal of the American Academy of Dermatology, 35(3), 1996, pp. 377-380
Background: Contact dermatitis from artificial nails made from self-cu
ring acrylic resins is occasionally reported. Recently, UV light-cured
products introducing new acrylics have become available. Objective: O
ur purpose was to identify relevant allergens in commercial light-curi
ng products by patch tests and to evaluate the efficacy of ''hypoaller
genic'' products by inclusion into the test series, Methods: Patients
wearing photobonded acrylic nails who had perionychial and subonychial
eczema were patch tested with an acrylate battery and ''hypoallergeni
c'' commercial products. Results: Triethyleneglycol dimethacrylate, hy
droxyfunctional methacrylates, and (meth)acrylated urethanes proved to
be relevant allergens in photobonded nail preparations. Methacrylated
epoxy resin sensitization was not observed. All ''hypoallergenic'' pr
oducts provoked positive reactions. Conclusion: The omission of irrita
nt methacrylic acid in W-curable products does not reduce the high sen
sitizing potential of new acrylates. In contrast to the manufacturers'
declarations, all ''hypoallergenic'' products continue to include acr
ylate functional monomers and therefore continue to cause allergic sen
sitization.