In the presented retrospective study incidence, age and breed distribu
tion of canine mammary gland tumors in the patient population of the S
mall Animal Clinic, School of Veterinary Medicine, Hannover, are exami
ned. In addition, survival rates and the frequency of tumor recurrence
and/or distant metastasis following surgical resection are shown. Com
prising 41.6 per cent of all neoplasms in the female dog, mammary glan
d tumors have to be considered very important especially in the older,
intact bitch. Of those mammary gland tumors that underwent histopatho
logical examination up to 75.6 percent were read out as being malignan
t, the adenocarcinoma and carcinosarcoma representing over half of tho
se cases. In 49.3 per cent of the cases that were followed up tumor re
currence and/or metastasis (mainly pulmonary) had occurred within one
year after surgery. 37 per cent of the dogs we were able to follow up
on died within the first year after tumor removal, in 90 per cent of t
hese cases the cause of death was reported to be directly related to t
he tumor. The adenocarcinoma of the mammary gland exhibited the most g
uarded prognosis. The presented and earlier studies demonstrate unsati
sfactory results in canine mammary gland tumor recurrence and rate of
metastasis which implies the necessity for additional therapeutic appr
oaches in this important canine neoplastic disease. This aspect is und
erlined by the fact that questioned owners exhibited very postive opin
ions towards post-operative chemotherapy in cases of malignancy. This
not only demonstrates a willingness to seriously consider such a treat
ment but also reflects a certain request for recent treatment modaliti
es for their animals. Further studies on peri- and post-operative ther
apy of canine malignant mammary gland tumors are mandatory.