THE AMES TEST - APPLICABILITY TO SMOKERS URINES

Authors
PELISSIER AL DUFFAUT F DEMEO MP BOTTA A
Citation
Al. Pelissier et al., THE AMES TEST - APPLICABILITY TO SMOKERS URINES, La Revue de medecine interne, 17(8), 1996, pp. 635-639
Citations number
15
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
17
Issue
8
Year of publication
1996
Pages
635 - 639
Database
ISI
SICI code
0248-8663(1996)17:8<635:TAT-AT>2.0.ZU;2-1
Abstract
The Ames test is a rapid and sensitive in vitro technique for detectin g mutagens by using Salmonella typhimurium hypersensibilized strains. We applied this assay to the study of smoker's urine mutagenicity. Eig hteen smokers and 18 non-smokers were investigated, Statistical analys is showed a significant increase of the smoker's urine mutagenicity. T he Ames rest could be used to determine the mutagenicity level of smok ers. Moreover, the results suggest the applicability of the Ames test to urines of ex-smokers and passive smokers.