Objective: To establish a treatment algorithm for reconstructing compl
ex midfacial defects. Design: Retrospective case series. Setting: Univ
ersity-based teaching hospital. Patients: Thirty-one consecutive patie
nts were treated from 1991 through 1995. The 18 males and 13 females w
ere aged 15 to 90 years (mean age, 58 years). The cause of the defect
included neoplasm (n=27) and trauma (n=4). Reconstruction consisted of
1 of 4 free flaps: rectus abdominis, radial forearm, fibula, or latis
simus dorsi. Aesthetic and functional results were determined by patie
nt questionnaires and physical examinations. Main Outcome Measures: Le
ngth of stay, postoperative morbidity and mortality, degree of aesthet
ic and functional restoration, and detection of tumor recurrence. Resu
lts: Twenty-seven (87%) of the 31 patients underwent reconstruction wi
th a single major procedure. All of the flaps survived. Postoperative
hospital stays averaged 14 days. Late tumor recurrence occurred in 7 (
23%) of the 31 patients and was promptly detected. Aesthetic and funct
ional results were rated good or excellent. in 77% (24/31) and 87% (27
/31) of patients, respectively. Of the 20 patients who underwent. alve
olar ridge resection, 16 (80%) received dental rehabilitation, 44% of
whom received osseointegrated implants into either a bone flap or rema
ining native bone. Osseointegrated implants were inset during the init
ial reconstruction 57% (4/7 patients) of the time. Conclusions: For co
mplex midfacial defects, free-flap transfer can be performed with a hi
gh degree of success, restoring both appearance and function in most p
atients. The only instance in which bone is necessary to reconstruct t
he midface involves those areas in which osseointegrated implants are
needed, ie, alveolar ridge (dental implant) and/or orbit (ocular prost
hesis). In such cases, the fibula osteocutaneous free flap is the flap
of choice. Otherwise, soft-tissue flaps are selected based on wound s
ize.