A number of factors have contributed to the growing incidence of funga
l nail infections, including an aging population, an expanding number
of immunocompromised patients, and increasing participation in fitness
-related activities. Although onychomycosis and other nail diseases ca
n adversely affect the appearance of the nail unit, the impact of such
nail disfigurement extends well beyond the aesthetic realm. In fact,
many patients with fungal nail infections experience serious physical,
psychosocial, and occupational effects as a result of this disease. I
n addition, onychomycosis is a serious health burden, particularly in
older persons, and has a major economic impact on the healthcare syste
m.