SYNTHESIS OF 3-FLUORO AZETIDINONE BY ELECTROPHILIC FLUORINATION

Authors
GENET JP DURAND JO ROLAND S SAVIGNAC M JUNG F
Citation
Jp. Genet et al., SYNTHESIS OF 3-FLUORO AZETIDINONE BY ELECTROPHILIC FLUORINATION, Tetrahedron letters, 38(1), 1997, pp. 69-72
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
1
Year of publication
1997
Pages
69 - 72
Database
ISI
SICI code
0040-4039(1997)38:1<69:SO3ABE>2.0.ZU;2-O
Abstract
An easy access to the 3-fluoroazetidinone 4a based on electrophilic fl uorination, is reported. The fluorination of the beta-lactam 7 with Di fferding's N-fluorosulfonimide proceeds stereoselectively, under mild conditions and in good yield. Copyright (C) 1996 Published by Elsevier Science Ltd