Ac. Rosen et B. Anegg, THE PRIMARY ANTIPHOSPHOLIPID ANTIBODY SYN DROME IN PREGNANCY - SUCCESSFUL PREGNANCY FOLLOWING INTRAVENOUS GAMMA-GLOBULIN TREATMENT, Geburtshilfe und Frauenheilkunde, 56(8), 1996, pp. 410-413
Primary antiphospholipid antibody syndrome is characterized by intraut
erine fetal death and arterial and/or venous thrombosis. The clinical
course of a 37-year-old pregnant woman with a history of eight previou
s miscarriages is presented. By application of intravenous immunoglobu
lin (Venimmun(R) Behringwerke Marburg/Lahn) a successful pregnancy cou
ld be accomplished. Diagnosis, immunologic pathomechanisms, possible t
reatment modalities as well as the obstetric management of this autoim
mune disease will be discussed.