F. Wierrani et al., BOTRYOID SARCOMA OF THE INFANT VAGINA - A SOFT-TISSUE SARCOMA WITH A HIGH PROBABILITY OF CURE, Geburtshilfe und Frauenheilkunde, 56(8), 1996, pp. 441-442
Although rare, sarcoma botryoides of the vagina in infants is a highly
aggressive soft tissue tumour. Former opinions suggesting exenterativ
e surgery and radiation to improve the dismal outcome in these young c
hildren, are outdated. Due to balanced therapies (topical tumourectomy
, chemotherapy and radiation adjusted to tumour stage) cure of these s
arcomas may be expected dependent on tumour stage, localisation and re
sponse to chemotherapy. The rate of complete remissions has increased
in recent years, We report on an eighteen-month old girl with complete
remission of tumour stage IIA who had been treated according to the C
WS 91 protocol. Diagnosis and treatment were performed in March 1994 a
t the age of six months. We observed the patient in complete remission
for 8 months (till September 1995).