Reliable prediction of metapopulation persistence in fragmented landsc
apes has become a priority in conservation biology, with ongoing destr
uction of habitat confining increasing numbers of species into network
s of small patches. A spatially realistic metapopulation model, which
includes the first-order effects of patch area and isolation on extinc
tion and colonization, has been tested, The distribution of an endange
red butterfly was successfully predicted on the basis of parameter val
ues estimated for a well-studied congeneric species. This modeling app
roach can be a practical tool in the study and conservation of species
in highly fragmented landscapes.