Mt. Kauppinen et al., ROENTGENOGRAPHIC FINDINGS OF PNEUMONIA CAUSED BY CHLAMYDIA-PNEUMONIAE- COMPARISON WITH STREPTOCOCCUS-PNEUMONIA, Archives of internal medicine, 156(16), 1996, pp. 1851-1856
Background: Pneumonia caused by Chlamydia pneumoniae or Streptococcus
pneumoniae cannot be reliably differentiated by clinical signs or symp
toms. Objective: To find differences in the roentgenographic patterns
of community-acquired pneumonia caused by C pneumoniae, S pneumoniae,
or both in hospitalized patients during a C pneumoniae epidemic in Fin
land. Methods: The patients were divided into 3 groups: 24 patients wi
th serologic evidence of C pneumoniae only; 8 patients with combined C
pneumoniae and S pneumoniae infection; and 13 patients with infection
caused by S pneumoniae only. The chest roentgenograms obtained on adm
ission to the hospital, during the hospital stay, and at follow-up vis
its were reevaluated by one of us (S.L.) who was unaware of the causat
ive organism. In the final study groups, other causes of community-acq
uired pneumonia were excluded by a large pattern of microbiological me
thods. Results: Bronchopneumonia was observed in 21 (88%) of the group
with C pneumoniae and 10 (77%) of the group with S pneumoniae (P=.67)
. Lobar or sublobar (air space) pneumonia was seen in 7 (29%) of the p
atients with C pneumoniae compared with 7 (54%) with pneumonia caused
by S pneumoniae. In the combined group, bronchopneumonia was seen as f
requently as in the group with C pneumoniae, and air-space involvement
was seen as frequently as in the group with S pneumoniae. The pneumon
ic shadowing was usually unilateral and in the lower lobes in all grou
ps. Of the patients in the C pneumoniae group, 17% had residual abnorm
alities at follow-up visits.