In this study the detectability of supratentorial brain infarctions by
CT with regard to the time interval after symptom onset and to the in
farction type and size was evaluated. 206 patients with supratentorial
brain infarctions of whom a CT scan was performed within 24 hours aft
er symptom onset were selected for this study. Signs of early ischaemi
a, infarction type and size were determined by two examiners, the diag
nosis was confirmed by follow-up CT's. Eighty-seven percent of the ter
ritorial infarctions were recognised, the rate of defection did not in
crease after the first hour. The hyperdense middle cerebral artery sig
n (HMCAS) was found in 40% of all MCA infarctions. It was however pres
ent in 83% within the first 90 minutes and in only 18% from hour 12 to
24. All lentiform nucleus-MCA infarcts and 95% of the larger MCA infa
rcts but only 77 (i.e. 68%) of the infarctions covering less than 33%
of the MCA territory, were detected. Among the haemodynamic infarction
s all watershed infarctions, but only 30 (i.e. 53%) of the terminal su
pply area infarctions were recognised. The detectability of supratento
rial brain infarctions therefore mainly depends on infarction type and
size. The detection rate of territorial infarctions after the first h
our corresponds with the infarction size, but not with the time interv
al. The HMCAS is the earliest sign of ischaemia; however, it is suffic
iently sensitive only within the first 90 minutes.