ISOLATION AND CHARACTERIZATION OF A BACTERIAL GROWTH-STIMULATING PEPTIDE FROM A PEPTIDE BOVINE HEMOGLOBIN HYDROLYSATE

Authors
ZHAO QY PIOT JM GAUTIER V COTTENCEAU G
Citation
Qy. Zhao et al., ISOLATION AND CHARACTERIZATION OF A BACTERIAL GROWTH-STIMULATING PEPTIDE FROM A PEPTIDE BOVINE HEMOGLOBIN HYDROLYSATE, Applied microbiology and biotechnology, 45(6), 1996, pp. 778-784
Citations number
39
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Applied microbiology and biotechnology → ACNP
ISSN journal
01757598
Volume
45
Issue
6
Year of publication
1996
Pages
778 - 784
Database
ISI
SICI code
0175-7598(1996)45:6<778:IACOAB>2.0.ZU;2-N
Abstract
A peptide with a bacterial-growth-stimulating activity was isolated fr om a bovine hemoglobin hydrolysate by reversed-phase high-performance liquid chromatography. Its primary structure and molecular mass. deter mined by amino acid analysis and fast-atom bombardment mass spectromet ry, were identical to those of fragment 48-52 (Ser-Thr-Ala-Asp-Ala) of the beta chain of bovine hemoglobin, The microbiological tests in sol id media demonstrated that this peptide exhibited a growth-stimulating activity on gram-negative bacteria.