NEW SYNTHETIC STRATEGY FOR THE SYNTHESIS OF 24-EPIBRASSINOLIDE

Authors
BROSA C PUIG R COMAS X FERNANDEZ C
Citation
C. Brosa et al., NEW SYNTHETIC STRATEGY FOR THE SYNTHESIS OF 24-EPIBRASSINOLIDE, Steroids, 61(9), 1996, pp. 540-543
Citations number
16
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Steroids → ACNP
ISSN journal
0039128X
Volume
61
Issue
9
Year of publication
1996
Pages
540 - 543
Database
ISI
SICI code
0039-128X(1996)61:9<540:NSSFTS>2.0.ZU;2-O
Abstract
The synthesis of (22E, 24R)-5 alpha-ergosta-2,22-dien-6-one (2), a key intermediate to the preparation of 24-epibrassinolide (1), was achiev ed through the 3,6-diketone 8 in a 40% overall yield in five steps sta rting from ergosterol (3).