Object: Depression is a common problem following a spinal cord injury
(SCI) and can greatly interfere with the rehabilitation process becaus
e of reduced energy, negative expectations, and social withdrawal. Und
erstanding various factors which influence a vulnerability to depressi
on may improve the diagnosis and treatment of depressive disorders and
can improve rehabilitation outcome. Method: A thorough literature sea
rch was conducted using Medline, PsychLit, PyschInfo, and Social Scien
ce Citation Index to identify relevant articles published between 1967
and 1995. Results: A diathesis-stress model is proposed to explain th
e increased risk of depressive symptoms after a SCI. Biological change
s associated with SCI and pre-existing cognitive biases may influence
the individual's vulnerability to stressful life events following the
injury. The nature and frequency of stressful life events following th
e injury can tax the individual's coping resources. Furthermore, the p
erceived quality of social support and the severity of conflict within
the family can influence the individual's adaptation. Conclusions: So
cial support and recent stressors should be assessed to identify patie
nts at high risk for depression. Patients are less likely to become de
pressed if their independence is fostered and they are encouraged to d
evelop new sources of self-esteem. Relatives can be counseled to help
maintain supportive relationships within the family.