C. Auwhaedrich et al., CHARACTERISTIC - DISTRIBUTION OF DEPOSITS IN RECURRENT GRANULAR CORNEAL-DYSTROPHY, German journal of ophthalmology, 5(3), 1996, pp. 132-136
Granular corneal dystrophy can recur after penetrating keratoplasty. I
n those cases as in the early primary manifestation of the disease, de
posits are found predominantly in the superficial corneal layers, Ar a
later stage, stromal deposits can also be seen. We describe an additi
onal particular location of deposits and correlate clinical with histo
logical findings in three corneas from two patients. Deposits were fou
nd mainly superficially within the graft and around the edge of the tr
ansplant along the scar between host and donor cornea. We suggest that
the deposits are of epithelial origin, though their production by str
omal cells cannot be excluded. Chemical interactions are discussed as
an explanation for the characteristic distribution of the deposits.