A 9-YEAR FOLLOW-UP-STUDY OF A POPULATION OCCUPATIONALLY EXPOSED TO VINYL-CHLORIDE MONOMER

Authors
FUCIC A BARKOVIC D GARAJVRHOVAC V KUBELKA D IVANIC B DABO T MIJIC A
Citation
A. Fucic et al., A 9-YEAR FOLLOW-UP-STUDY OF A POPULATION OCCUPATIONALLY EXPOSED TO VINYL-CHLORIDE MONOMER, Mutation research. Section on environmental mutagenesis and related subjects, 361(1), 1996, pp. 49-53
Citations number
21
Categorie Soggetti
Genetics & Heredity","Environmental Sciences
Journal title
Mutation research. Section on environmental mutagenesis and related subjects → ACNP
ISSN journal
01651161
Volume
361
Issue
1
Year of publication
1996
Pages
49 - 53
Database
ISI
SICI code
0165-1161(1996)361:1<49:A9FOAP>2.0.ZU;2-4
Abstract
The presence of structural chromosome aberrations and sister chromatid exchange frequencies (SCE) were studied in lymphocytes from 28 male s ubjects occupationally exposed to vinyl chloride monomer for a period of 9 years, A significant increase in chromosomal damages and elevated SCE frequencies was detected during the third and fourth year of the follow-up study. During the last 2 years, all examined parameters are approaching control values, This is a result of decreasing vinyl chlor ide monomer concentrations in the working environment without interrup ting the working process.