REGRESSION OF AIDS-RELATED KAPOSIS-SARCOMA DURING THERAPY WITH THALIDOMIDE

Authors
SOLER RA HOWARD M BRINK NS GIBB D TEDDER RS NADAL D
Citation
Ra. Soler et al., REGRESSION OF AIDS-RELATED KAPOSIS-SARCOMA DURING THERAPY WITH THALIDOMIDE, Clinical infectious diseases, 23(3), 1996, pp. 501-503
Citations number
13
Categorie Soggetti
Microbiology,Immunology,"Infectious Diseases
Journal title
Clinical infectious diseases → ACNP
ISSN journal
10584838
Volume
23
Issue
3
Year of publication
1996
Pages
501 - 503
Database
ISI
SICI code
1058-4838(1996)23:3<501:ROAKDT>2.0.ZU;2-Q
Abstract
A 14-year-old girl with HIV infection and subcutaneous Kaposi's sarcom a (KS) received thalidomide therapy for oral ulcers, resulting in regr ession of KS lesions, disappearance of KS-associated herpesvirus (KSHV ) DNA from blood, and reduced viral load in tumor tissue. Administrati on of granulocyte colony-stimulating factor resulted in clinical exace rbation of KS and reappearance of KSHV DNA in blood.