D-CYCLOSERINE BIASES ENRICHMENT FOR AUXOTROPHIC MUTANTS OF ZYMOMONAS-MOBILIS

Authors
PENCREACH G AITABDELKADER N JOSET F BARATTI JC
Citation
G. Pencreach et al., D-CYCLOSERINE BIASES ENRICHMENT FOR AUXOTROPHIC MUTANTS OF ZYMOMONAS-MOBILIS, FEMS microbiology letters, 142(2-3), 1996, pp. 167-171
Citations number
8
Categorie Soggetti
Microbiology
Journal title
FEMS microbiology letters → ACNP
ISSN journal
03781097
Volume
142
Issue
2-3
Year of publication
1996
Pages
167 - 171
Database
ISI
SICI code
0378-1097(1996)142:2-3<167:DBEFAM>2.0.ZU;2-V
Abstract
Contrary to its effect on rich medium, D-cycloserine showed no bacteri cidal effect on Zymomonas mobilis cells cultured on mineral medium. Ad dition of a mixture of glycine and glutamic acid to the mineral medium restored its bactericidal action. However, mutant enrichments run in these conditions were biased, with mostly methionine mutants isolated. A decrease of the D-cycloserine concentration only reduced the bias.