STRUCTURAL CHARACTERIZATION OF HUMAN AD4BP (SF-1) GENE

Authors
OBA K YANASE T NOMURA M MOROHASHI K TAKAYANAGI R NAWATA H
Citation
K. Oba et al., STRUCTURAL CHARACTERIZATION OF HUMAN AD4BP (SF-1) GENE, Biochemical and biophysical research communications, 226(1), 1996, pp. 261-267
Citations number
24
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
226
Issue
1
Year of publication
1996
Pages
261 - 267
Database
ISI
SICI code
0006-291X(1996)226:1<261:SCOHA(>2.0.ZU;2-1
Abstract
Ad4BP (or steroidogenic factor 1, SF-1) has been implicated to be an e ssential transcriptional factor for steroidogenesis as well as for the development of the reproductive axis. We elucidated the structure of the human Ad4BP gene. The gene is about 30 kb long and is split into 7 exons including a non-coding exon 1. The deduced amino acid sequence of the human Ad4BP consists of 461 amino acid residues and was highly homologous to those of other mammalian species. (C) 1996 Academic Pres s, Inc.