Bioavailability of vitamin E in three fortified breakfast cereals and
dose-response relationships among dietary vitamin E and selected bioch
emical indices were investigated using a rat depletion-repletion model
. Response criteria included concentrations of oc-tocopherol in plasma
, red blood cells, liver, heart, and adipose tissue, and plasma pyruva
te kinase activity. Bioavailability of vitamin E in whole grain cereal
and corn flakes was generally comparable to that of the tocopheryl ac
etate standard. Bioavailability of vitamin E in bran flakes was lower
than that of the standard based on four of the criteria. A food matrix
effect in bran flakes resulted in the lower bioavailability.