UNCOVERED - THE FAMILY RELATIONSHIP OF A T-CELL-MEMBRANE PROTEIN AND BACTERIAL TOXINS

Authors
KOCHNOLTE F HAAG F KASTELEIN R BAZAN F
Citation
F. Kochnolte et al., UNCOVERED - THE FAMILY RELATIONSHIP OF A T-CELL-MEMBRANE PROTEIN AND BACTERIAL TOXINS, Immunology today, 17(9), 1996, pp. 402-405
Citations number
30
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
17
Issue
9
Year of publication
1996
Pages
402 - 405
Database
ISI
SICI code
0167-5699(1996)17:9<402:U-TFRO>2.0.ZU;2-V
Abstract
Mono-ADP-ribosylation was originally discovered as the mechanism by wh ich diphtheria toxin inactivates protein synthesis. It is now apparent that higher organisms use analogous mechanisms to regulate endogenous metabolism. Here, the relationship between bacterial toxins and verte brate mono-ADP ribosyltransferases is explored.