CASE-REPORT - 17-ALPHA-HYDROXYLASE 17,20-LYASE DEFICIENCY - A RARE CAUSE OF ENDOCRINE HYPERTENSION/

The combination of hypertension, hypokaliemia, and male pseudohermaphr oditism or amenorrhea must prompt a search for a rare adrenal enzymati c defect, 17 alpha-hydroxylase/17,20-lyase deficiency. This is a repor t of the observation of a male patient in whom this rare deficit was d iagnosed in adulthood on the basis of lifelong ambiguous external geni talia, hypogonadism, severe hypertension, bilateral adrenal hyperplasi a, and biological markers evoking an excess of mineralocorticoids with out hyperaldosteronism.