ELECTROPHYSIOLOGICAL PROPERTIES OF RAT SUBICULAR NEURONS IN-VITRO

The electrophysiological properties of 46 bursting cells and 39 regula r firing cells were studied in the subiculum of rat combined hippocamp al-entorhinal cortex slices. In bursting cells we found a significantl y higher resting membrane potential than in regular firing cells. Upon hyperpolarization both cell types expressed a delayed inward rectific ation with a subsequent afterdepolarization. While in regular firing c ells longer lasting depolarizing current injection caused a train of a ction potentials with a rather marked decline of discharge frequency, bursting cells displayed only little frequency accommodation. Regular firing cells-usually displayed a fast and a slow afterhyperpolarizatio n following a train of action potentials, while bursting neurons prese nt only a slow afterhyperpolarization. Copyright (C) 1996 Elsevier Sci ence Ireland Ltd.