DIABETIC-RETINOPATHY - A REVIEW FOR THE PRIMARY-CARE PHYSICIAN

Hyperglycemia can result in key biochemical reactions that may contrib ute to thickening of basement membranes, dysfunction of pericytes and endothelial cells, and closure of retinal vessels. The Diabetes Contro l and Complications Trial has proved the value of good glycemic contro l in preventing retinopathy and/or delaying its progression. The prima ry care physician has a crucial role in translating these results into practice. Recognition and management of other risk factors, such as p roteinuria, smoking, and hypertension, are easily done in the primary care setting, Also, appropriate referral to an ophthalmologist for ret inal evaluation and treatment is both necessary and cost effective in reducing the burden of this: devastating complication of diabetes.